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Moreover, IRF3-mediated production of type I IFN was suggested to be the driving force for the observed STAT1 phosphorylation and expression of innate immune response genes such as IFIT1 in breast cancer type 2 susceptibility protein (BRCA2)-deficient H1299 cells

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Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase

Plant Physiol 165:854865 Hernndez I, Chacn O, Rodriguez R, Portieles R, Lpez Y, Pujol M, Borrs-Hidalgo O (2009) Black shank resistant tobacco by silencing of glutathione S-transferase