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Overall, increased oxygen consumption, energy production, and lactic acid production during high-intensity exercise can increase free radicals and oxidative stress, which can cause damage to cells and tissues if not adequately neutralized by the bodys antioxidant defense system

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B12 deficiency can lead to severe and potentially irreversible neurological damage if misdiagnosed or inadequately treated

A.Schumacher DimechA.Santuccione ChadhaA.et al (2018)