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Abstract Tumor metabolic reprogramming is a highly complex process that enables tumor survival in the presence of limited nutrients, involving multiple signaling pathways, non-coding RNAs (ncRNAs), and transcription factors

doi: 10.1016/J.IJID.2022.03.006 23 MendelsonMNelJBlumbergLMadhiSADrydenMStevensWet al

The reactive oxygen species (ROS) generation is directly associated with intracellular Ca 2+ in plants (Marcec et al., 2019

Moreover, such studies will further promote the research and development of drugs related to glutamine metabolism inhibition and thus provide more treatment options and hope for cancer patients