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Williams, K

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Upon activation, Nrf2 translocates to the nucleus, binds specifically to the Antioxidant Response Element (ARE) and induces transcription of downstream genes (Baird and Dinkova-Kostova, 2011) (Figure 2B)

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381 Similarly, RTK inhibitors targeting PDGFR (e.g., olaratumab and crenolanib) and c-KIT (avapritinib) show promising BBB penetration but are hindered by resistance mechanisms

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Professional skin whitening treatments deliver faster, more noticeable results compared to home remedies

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