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Standard capsules are often broken down by stomach acid before they can be absorbed

In the German manufacturers PIL (Patient information leaflets) for hydroxocobalamin they state that B12 can be given subcutaneously or intramuscularly, so why when other countries understand that B12 can be given by both routes did the UK only license it for intramuscular

If you have pernicious anaemia, your immune system attacks healthy cells in your stomach, preventing your body absorbing vitamin B12 from the food you eat

doi: 10.3389/fnut.2026.1783979 Received 09 January 2026 Revised 26 February 2026 Accepted 09 March 2026 Published 27 March 2026 Volume 13 - 2026 Edited by Zhao-Jun Wei, North Minzu University, China Reviewed by Jong-Sang Kim, Kyungpook National University, Republic of Korea Hongcai Li, Northwest A&F University, China Updates Copyright 2026 Feng, Zhao, Liu, Hua, Zheng, Wang, Xia and Li