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History of scurvy and the discovery of vitamin C Although scurvy has been known since ancient times (Clemeston, 1989), it became a notable cause of large scale deaths in the last five hundred years

It is noteworthy that although the significant enrichment of ferroptosis-related genes in oligodendrocytes and the changes in Mt1 and Ca 2+ content in astrocytes suggest the activation of the ferroptosis process in both cell types, our prior snRNA-seq data indicated a significant increase in the number of oligodendrocytes and astrocytes under PD conditions

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