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To estimate PCD prevalence, we excluded neonatal patients identified or suspected of PCD, leaving 17,864 (7,333 males and 10,531 females) neonates (Figure 1B)

Prolonged ER stress ultimately leads to apoptosis or ferroptosis and thus determines cellular outcome

In contrast, co-treatment with 5-Azacytidine, which has previously been shown to act synergistically with Venetoclax therapy by disrupting energy metabolism 56 , had no impact on intracellular Venetoclax concentrations