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Treatment by exogenous ethylene, as a common postharvest practice to trigger the ripening of mature green fruits before placing them on the shelf, caused a 24% and 51% folate increase in tomatoes and bananas, resp., a 26% folate decrease in papayas, and no change in avocados, compared to non-treated fruits 531

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In addition, it was noted that both BP and DOX work synergistically and upregulate the expression of apoptotic genes and proteins and eventually decrease the volume of tumor cells while decreasing the level of nitric oxide and estrogen and downregulating the level of pro-inflammatory cytokines in mice models with induced 4 T1 breast tumors