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Both BacA and IcL colonized liver and spleen of the intraperitoneally infected mice, with no statistically significant difference in GE/g in liver and spleen between mice infected with BacA and IcL compared to positive controls with average of 2.310 7 , 2.210 6 , and 5.610 6 CFU/g, respectively ( Figure 3 )

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Indomethacin Indomethacin, an NSAID that participates in both innate and adaptive immunity [131], has been shown to reduce the proportion of M.tb antigen-triggered Tregs, reactions of M.tb specific cytokines, and proliferation of T cells in active TB