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doi: 10.1093/humrep/dez019

5 Conclusions 1) This retrospective study provides the first in vivo evidence that DARA monotherapy, beyond its cytotoxic effects, modulates the secondary enzymatic functions of CD38 in MM, altering ADO and INO production and supporting a model of antibody-driven purinergic remodeling

Patience during this early phase prevents premature conclusions about effectiveness

This analysis is also the first to include data from recently published clinical trials of tirzepatide following its approval for the treatment of obesity