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As a prodrug form of 5-FU, capecitabine is used as monotherapy in a variety of advanced or metastatic cancers

Its N-terminal mART domain connects via a hinge and extensive interface to two tandem C-terminal -trident subdomains (D2 + D3) ( 2.3 Lipid-associated membrane proteins LAMPs serve as a key interface for pathogenhost interactions and function as potent proinflammatory molecules

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