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68 For clinical observation, the blood pressure must be high enough to cause red blood cell extravasation into the surrounding interstitial tissue, with leaked blood accumulating sufficiently near the skin surface to be visible

Pre-existing risk factors common in the diabetes population further compound concern: Older age (reduced intrinsic factor production) Autoimmune conditions (pernicious anaemia, thyroid disease) Previous gastric surgery or gastrointestinal disorders Vegetarian or vegan dietary patterns There is no established link between semaglutide pharmacology and B12 metabolism in the MHRA-approved product information, but the clinical context in which Ozempic is prescribed creates a population where B12 awareness is prudent

Some are well established in medicine