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2017;41:591604.e7

135,136 Moreover, several reports have suggested that an accumulation of Cu promotes aggregation of the HTT protein and interacts with histidine residues at the N-terminus of the protein

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DHODH in the inner mitochondrial membrane inhibits lipid peroxidation in the mitochondria by reducing CoQ 10 to CoQ 10 H 2 , indicating that DHODH can be a novel therapeutic target in cancer therapy by inducing ferroptosis