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Description

Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5

Nature 638 , 591592 (2025)

doi: 10.1016/j.lfs.2016.02.029

Informed Consent and Patient Education Informed consent discussions for BPC-157 use should clearly communicate the investigational nature of the peptide, lack of FDA approval, limited human safety and efficacy data, and the reliance on animal studies for much of the supporting evidence