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doi: 10.1016/j.immuni.2018.03.013 172 MaLGengJChenWQinMWangLZengY

In MPTP-treated neuronal cultures, paeoniflorin restored cell viability, normalized elevated intracellular Ca 2+ , and decreased apoptosis markers relative to untreated controls (38)

Furthermore, aescin substantially reduced cardiac enzymes to levels close to normal, indicating its potential to prevent membrane breakdown and subsequent enzyme leakage 111,112