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Sulfa drugs and the skin

Research indicates that the introduction of epoxy groups primarily inhibits apoptosis by stabilizing mitochondrial function, while functional groups such as carboxyl, carbonyl, or hydroxyl groups act as secondary pharmacophores, significantly enhancing free radical scavenging efficiency through electron delocalization effects ( The protective effect of rhodioloside, the primary component of Rhodiola crenulata (Hook

This was not unexpected due to the small sample size involved but this would warrant further investigation in a larger cohort and in serial biopsies after each chemotherapy cycle

Ahirwar, S