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With revolutionary advancement in formulation biotechnologies, particularly groundbreaking achievements in strain stability enhancement and bioactivity amplification, alongside personalized probiotic combination engineering for CKD populations, probiotics are destined to assume transformative leadership roles in future nephrology therapeutics

Once activated, mTORC1 phosphorylates two critical downstream targets: p70S6K (70-kDa ribosomal protein S6 kinase) and 4E-BP1