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Circulation 142 , 21382154 (2020)

Under certain conditions, twice or thrice-fold oxidation of the thiol group of GSH, resulting in sulphinic or sulphonic acid (GSO 2 H and GSO 3 H, respectively), pose a problem for the cellular recycling mechanisms

Since some adverse effects such as serious infections and skin cancers were reported, additional evaluation of the safety profile of this drug is needed (Gordon 2012

Studies have shown that oral collagen can be absorbed at rates as high as 63%, compared to 1-2% for other oral peptides.12 13 Injectable collagen peptides are available, too, but surveys show a large proportion of the population would prefer a less invasive method.14 BPC-157 is another peptide that boasts good oral bioavailability, but the same cant be said about its frequent companion, TB4.15 16 Because we recommend BPC-157 and TB4 in combination, and because BPC-157 can be hard to find in oral form, BPC alone failed to earn our designation as the easiest-to-use peptide