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All these distinct sex-dependent DNA methylation profiles are essential for male gametogenesis as demonstrated by reports that loss of function of DNMT3A and 3B leads to an arrest in meiosis, an overexpression of repeated elements such as LINEs (long interspersed nuclear elements) and IAP (intracisternal A particles) and, a loss in spermatocytes via apoptosis

Chemical Research in Toxicology 33, 25152526

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