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Others reported studies using AD mouse models fed a diet including deuterated 11,11-D 2 -linoleic acid ethyl ester (D 2 -LA) and 11,11,14,14-D 4 -alpha-linolenic acid ethyl ester (D 4 -ALA) in their diets for a sufficient period such that the phospholipids in brain became rich in deuterated fatty acids with allylic deuterium atoms in the indicated unsaturated fatty acids of phospholipids (127, 128)