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Zhan CD, Sindhu RK, Pang J, Ehdaie A, Vaziri ND

After preconditioning, heat-stressed corals improve the ability to maintain cellular redox homeostasis through BI-1-mediated glutathione reductase overexpression which prevents the accumulation of oxidative stress markers, avoids the activation of programmed cell death and results in prolongated coral-algal symbiosis

A.LiC.ZhangX.SinhaM.et al (2006)

For instance, the synergistic action of BRSV and Histophilus somni downregulated tight junction proteins and stimulated the aberrant secretion of matrix metalloproteinases (notably MMP1 and MMP3), thereby accelerating structural degradation and inflammatory infiltration 101