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B12 is different than many other vitamin nutritional deficiencies in that it is only found in animal-based food products such as meat, dairy, and eggs which makes this a nutrient to be especially vigilant of for vegetarians and vegans

3) Skin cleaning and local numbing The skin is cleaned with antiseptic, and a small amount of numbing medicine is injected to make the procedure more comfortable

Given the absence of demonstrated abnormalities in fibril morphology or collagen synthesis, this mechanism may be the most plausible