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These modifications were designed to: Increase molecular stability Reduce rapid degradation Extend systemic exposure Support prolonged receptor engagement These approaches are commonly used throughout peptide research when investigators seek to improve pharmacokinetic characteristics

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At baseline, the average trial participant had 13% scalp coverage

These models could further be leveraged to investigate if NSC-secreted factors modulate the gut microbiomes metabolic output or vice versa, providing a mechanistic link between the central and peripheral effects observed in our study