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[DOI] [PubMed] [Google Scholar] 65.Knezevic M., Gojkovic S., Krezic I., Zizek H., Malekinusic D., Vrdoljak B., Knezevic T., Vranes H., Drmic D., Staroveski M., et al

For arthritis specifically, semaglutide has evidence from the STEP-9 knee osteoarthritis trial and studies on rheumatoid arthritis joint outcomes, while tirzepatide has shown roughly a 33% reduction in hsCRP and an 18% reduction in IL-6 (key inflammation markers) in meta-analyses

Maybe it is a torn rotator cuff that wont heal, a knee that screams when you squat, or a tendonitis flare-up that has turned chronic

By 2024, a comprehensive review suggested the figure could be as high as 29%