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Gastroenterology 122(6):16491657 Tilg H, Diehl AM (2000) Cytokines in alcoholic and nonalcoholic steatohepatitis

identified three HCC subtypes (iHCC1-3) through a comprehensive analysis of The Cancer Genome Atlas-Liver Hepatocellular Carcinoma (TCGA-LIHC) dataset, and demonstrated that SLC13A3 mRNA expression is substantially high in the iHCC2 subtype with a high incidence of CTNNB1 mutations 8

3 Pharmacological treatments 3.1 Corticosteroids Glucocorticoids play a crucial role in the growth and development, while corticosteroids, as synthetic counterparts of glucocorticoids, exhibit properties of anti-inflammatory and immunosuppressive ( 3.1.1 Triamcinolone acetonide Triamcinolone acetonide, a versatile and widely utilized medication belonging to the class of corticosteroids, is available in a diverse range of pharmaceutical forms to cater to different medical needs and modes of application, including ointments, gels, mouthwashes, sprays, and pastes, which is most frequently medication employed for the treatment of mucosal lesions ( Triamcinolone acetonide can reduce the expression of IL-9 in the lesions, leading to the decline of MMP9, to relieve the symptoms of OLP ( Specific patient populations, particularly those grappling with persistent or intricate medical conditions, might require the continuation of this medication's use over an extended period

Temporary effects may include mild bruising, tenderness at the insertion site, or occasional light-headedness