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One report suggested that frataxin promotes the interaction between NFS1 and substrate (Pandey et al., 2013), while frataxin was reported to promote sulfide transfer from NFS1 to ISCU1 (Parent et al., 2015)

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It achieves this by directly scavenging reactive oxygen species (ROS), such as hydroxyl radicals and superoxide anions, which are unstable molecules that can tear apart cellular membranes and damage DNA

The market basket used for the LTCH PPS includes both operating and capital-related costs of LTCHs because the LTCH PPS uses a single payment rate for both operating and capital-related costs