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Considering these pathways, flavonoids may be therapeutic candidates for asthma, not only for their protective effects as antioxidants but also for their modulatory effects on cell signaling cascades related to inflammation and lung pathology (103)

Synthetic -tocopherol, which is often found in fortified food and nutritional supplements and usually labeled all - rac --tocopherol or dl --tocopherol, include all eight possible stereoisomers of -tocopherol (see Forms and Function)

Key structural alterations include disrupted mitochondrial morphology, severe ultrastructural damage, and depletion of mitochondrial DNA (mtDNA)

doi: 10.1038/s41586-020-2229-5 51