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The chances of intravascular occlusion with this product is extremely low (1 case 2022 out of 4+ million treatments), possibly the rheology of this injectable follows so well that end aa occlusion is v v rare, however animal studies should come out in the next few years to determine if this is the case

It has been efficient in increasing the TDDs with varying molecular weights including small (fentanyl, orcalcein) to high molecular weight drugs weighing up to 40 kDa

Your provider should discuss bioavailability when considering this approach

She suggested adding a specific substance, diethylaminoethyl (DEAE)-dextran, to the agar to neutralise the anticomplementary effect