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A., Sokolov, A

constructed an histone deacetylases score based on the expression level of histone deacetylases in GC to characterize the TME and predict immunotherapy efficacy 34

Despite these constraints, innovations in genetic engineering and immunocompromised humanized mice can bring preclinical studies closer to clinical reality

For bacteria, iron is also a co-factor in iron-containing proteins in redox reactions, metabolic pathways, and electron transport chain mechanisms (77)