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*Correspondence: Yang Zhao [email protected] Zhu [email protected] This article was submitted to Parkinson's Disease and Aging-related Movement Disorders, a section of the journal Frontiers in Aging Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Oxidized low-density lipoprotein (oxLDL) and endothelial dysfunction are key contributors to atherosclerosis, and MnSOD activity has been shown to reduce oxLDL-induced apoptosis in macrophages 253,254 , protect against endothelial dysfunction 255,256 , and inhibit LDL oxidation by endothelial cells 257

Barker TA, Massett MP, Korshunov VA, Mohan AM, Kennedy AJ, Berk BC Hypertension

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