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Furthermore, PD patients with diabetes exhibited higher subscores for postural instability and gait difficulties after controlling for dopaminergic denervation in the SN and striatum ( t = 3.81, P = 0.0005) [32] Apart from motor symptoms, PD is characterized by a wide variety of non-motor features, including dementia, depression, sleep disturbance, orthostatic hypotension, and psychotic symptom [1]

The following section provides a detailed review of the major chemical constituents and their pharmacological activities in Scrophulariae Radix

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This enzyme metabolizes many medications, creating opportunities for drug interactions