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This phenomenon was further corroborated by elevated concentrations of glycolytic metabolites in the vastus lateralis muscle (74)

Ben Allsop, the Research Associate at the University College London, UK, discusses this topic in the scientific talk: Simulating ischemia-reperfusion injury in vitro as a potential method for drug screening. In his talk, he also compares the different myocardial injury models, demonstrating that the CLARIOstar Plus with ACU reaches 0.1 % O 2 in around 45 minutes, much faster than any other system (e.g., a hypoxic chamber requires 120 minutes to get to 1% O 2 )

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although, the individual RCTs suggested a benefit of acetyl-L-carnitine compared to placebo in improving neurological findings