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SKU: 21876350594
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Description

Tesofensine is currently in clinical development for the treatment of obesity, however, the pharmacological basis for its strong effect in obesity management is not clarified

Potential Risks and Solutions Lack of Human Clinical Trials Risk: Much of the data on Dihexa comes from animal studies or user anecdotes, leaving uncertainties about long-term safety

The purified recombinant SsTyrA a D208N enzyme (Figure S3) drastically decreased its original ADH activity (Figure 4A), but now exhibited PDH activity (Figure 4B), with a slight alteration in cofactor specificity in the mutant compared to Wt (Figure S4)