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Detoxification enzymes of phase II compete with the activating enzymes of phase I to restrict the generation of electrophiles and catalyze the conversion of these electrophilic molecules to inactivate conjugates, making them more soluble in water and more easily get excreted from the body

HGF/c-Met signaling deficits have been documented in schizophrenic brain tissue, making this the most mechanistically specific target

Hagebeuk EE, Koelman JH, Duran M, et al

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