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Specifically, AHK-Cu might increase the expression of Bcl-2, an anti-apoptotic molecule, while reducing the levels of Bax, a pro-apoptotic counterpart

As illustrated by the structure of the infectious virion, the cleaved E3 associates with the AB strand mainly through hydrophobic interactions, stabilizing E2 DB under acidic conditions during Golgi processing

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Supplementary material The Supplementary Material for this article can be found online at: Glossary Akt Protein Kinase B Bax BCL2-Associated X protein Bcl-2 B-cell lymphoma/leukemia-2 DISC Death-inducing signaling complex EMs Endometriosis ER Endoplasmic reticulum ERK Extracellular signal-regulated kinase FADD Fas-associated death domain GPX4 Glutathione Peroxidase 4 GSDMD Gasdermin D GSH Glutathione HO-1 Heme Oxygenase-1 IhOESCs Immortalized human ovarian endometriotic stromal cell lines IL-6 Interleukin 6 IL-1 Interleukin-1 LC3 Light Chain 3 MAPK Mitogen-activated protein kinase MDA Malondialdehyde MLKL Mixed lineage kinase domain-like protein MMP Matrix metalloproteinase mTOR mammalian target of rapamycin NF-B Nuclear Factor kappa-B NLRP3 NLR family pyrin domain-containing protein 3 Nrf2 Nuclear factor erythroid 2-related factor 2 PCD Programmed cell death PI3K Phosphatidylinositol 3-kinase RIPK Receptor-interacting protein kinase ROS Reactive oxygen species SOD Superoxide dismutase TGF- Transforming Growth Factor Beta Receptor TNF- Tumor necrosis factor- HIF-1 Hypoxia-Inducible Factor -1 References 1 AnM.FuX.MengX.LiuH.MaY.LiY.et al (2024)