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Due to the Complexity of FD diagnosis and treatment, there remains a scarcity of high-quality clinical studies pertaining to FD, which further restricts research into the exact role of PPIs in FD

Another challenge lies in the reliance on animal models in experiments, as these models differ significantly from humans in genetic background and disease heterogeneity, and there is still a lack of result validation in human patients

The combination is utilized in research for investigating possible synergy on pathways such as angiogenesis and tissue regeneration

Endometrial organoid cell atlas vis--vis the cycling endometrial epithelium While morphological and functional assays have demonstrated their resemblance to primary endometrial epithelium, the precise cell-type composition of endometrial organoids remains to be fully elucidated