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This is because of the observed risk for myocarditis and pericarditis after receipt of ACAM2000 orthopoxvirus vaccine and COVID-19 vaccines, and the hypothetical risk for myocarditis and pericarditis after Jynneos vaccine

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Evidence supports a role for supplemental folic acid and vitamin B12 for lowering homocysteine levels, however this does not mean that these supplements will decrease the risk of cardiovascular disease