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Per the applicant, patients in the hospital for their initial TECVAYLI TM treatment will receive three doses subcutaneouslya 0.06 mg/kg loading dose, a 0.30 mg/kg loading dose, and the first 1.5 mg/kg treatment doseduring the hospital stay

This aligns with prior research indicating that colorectal cancer exhibits a glycolytic phenotype, which could reduce its dependence on glutamine metabolism for antioxidant defense 35 and reflects the well-established metabolic heterogeneity of CRC, in which different subtypes rely on distinct metabolic programs

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10.3389/fphar.2019.01040 Front Pharmacol