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Growth factors and Parkinson Several neurotrophic and growth factors have been shown to protect dopaminergic neurons and glial cells against induced excitotoxicity by the activation of specific signaling pathways that are responsible for cell survival and axonal sprouting [31,32]

The injection process is generally swift, and while some might experience a slight pinch or pressure upon needle insertion, the overall procedure is designed to be as minimally invasive and comfortable as possible

For example, in a model of sepsis-induced AKI, lipotoxin A4 was used to inhibit the senescence of renal tubular cells, and renal function was recovered (Li and Lerman, 2020)

doi: 10.1016/j.micpath.2022.105725 64 Goguyer-DeschaumesR.WaeckelL.KillianM.RochereauN.PaulS