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Starting in 2018, WADA clarified the use the language mentioned above, having changed hospital admissions to hospital treatment, and clinical investigations to clinical diagnostic investigations. Hospital treatment includes treatment or admission at a physical hospital named as such

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Its contribution to weight loss is less straightforward than GLP-1's and is still an active area of research, but targeting both receptors simultaneously appears to produce greater weight reduction than GLP-1 alone, which is the basis for tirzepatide's dual mechanism