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Wang H, Sun Y, Xiao FJ, Zhao X, Zhang WY, Xia YJ, et al

Tardive dyskinesia: are first signs reversible

The only alteration we made was the replacement of Met1 by its bioisostere norleucine (Nle) to avoid the notorious oxidation of the Met1 thioether moiety, leading to different molecular weights (M, M+16Da and M+32Da) for a single type of Ub protein, which is detrimental to MS analysis and quantification