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The reason for the toxicity order is attributed to the decrease of the concentration of Zn 2+ ions by the generation of precipitates and zinc complexes in different media

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In the present study, we investigated a single affected individual (III-7) with MTHFR deficiency demonstrating severe features such as microcephaly, delayed growth, ophthalmic issues, non-obstructive hydrocephalus, elevated blood homocysteine level, and elevated plasma methionine levels

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