Growth Hormone Secretagogue Selective GHS receptor agonist for growth hormone research Ipamorelin is a synthetic pentapeptide growth hormone secretagogue (GHS) that selectively activates the ghrelin/GHS receptor
Combining it with microneedling, for example, dramatically amplifies results: the needling creates microchannels that allow GHK-Cu to penetrate deeply into the dermis, while the peptide accelerates healing and maximizes the collagen-induction response

A suitable dose per day for a ghrelin mimetic of the invention can be in the range of from about 1 ng to about 10,000 mg, about 5 ng to about 9,500 mg, about 10 ng to about 9,000 mg, about 20 ng to about 8,500 mg, about 30 ng to about 7,500 mg, about 40 ng to about 7,000 mg, about 50 ng to about 6,500 mg, about 100 ng to about 6,000 mg, about 200 ng to about 5,500 mg, about 300 ng to about 5,000 mg, about 400 ng to about 4,500 mg, about 500 ng to about 4,000 mg, about 1 g to about 3,500 mg, about 5 g to about 3,000 mg, about 10 g to about 2,600 mg, about 20 g to about 2,575 mg, about 30 g to about 2,550 mg, about 40 g to about 2,500 mg, about 50 g to about 2,475 mg, about 100 g to about 2,450 mg, about 200 g to about 2,425 mg, about 0.300 g to about 2,000, about 400 g to about 1,175 mg, about 500 g to about 1,150 mg, about 0.5 mg to about 1,125 mg, about 1 mg to about 1,100 mg, about 1.25 mg to about 1,075 mg, about 1.5 mg to about 1,050 mg, about 2.0 mg to about 1,025 mg, about 2.5 mg to about 1,000 mg, about 3.0 mg to about 975 mg, about 3.5 mg to about 950 mg, about 4.0 mg to about 925 mg, about 4.5 mg to about 900 mg, about 5 mg to about 875 mg, about 10 mg to about 850 mg, about 20 mg to about 825 mg, about 30 mg to about 800 mg, about 40 mg to about 775 mg, about 50 mg to about 750 mg, about 100 mg to about 725 mg, about 200 mg to about 700 mg, about 300 mg to about 675 mg, about 400 mg to about 650 mg, about 500 mg, or about 525 mg to about 625 mg

The lifetime and first-day decay are improved by 2.5 and 3 times, respectively