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While safety monitoring was comprehensive, the trials were not specifically designed to detect rare adverse effects that might occur at rates lower than 1-2%, which would require much larger participant numbers

Integration with broader wellness services, including testosterone optimization and IV therapy

Both univariate and multivariate Cox proportional hazards regression analyses were performed to assess the prognostic value of the drug-related signature (DRS) scores, adjusting for potential confounders

After 24 hours from the first trial, a second trial is performed by placing the animal in the same container, but for 5 minutes