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succeeded in creating the first biologically active and boronated TATE analogs by using the ortho-carborane-containing building block 4-(O-methylencarboranyl)-benzoic acid (BBB1), which was coupled either directly to the N-terminus or by glycinylsarcosine spacers of different length (Figure 10B) (Betzel et al., In addition to these PDCs, the hY 1 R preferring peptide [F 7 ,P 34 ]-NPY has been recently described as a suitable target in BNCT

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Because C-peptide is released concurrently with insulin, its measurement in the blood or urine measures the amount of C-peptide in the blood or urine , serving as an indirect yet highly accurate indicator of endogenous insulin production