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Key Points Penile fracture is a rare surgical emergency It involves the traumatic rupture of corpus cavernosa and the tunica albuginea in an erect penis Presents typically during intercourse with a popping sound, pain, and immediate detumescence Diagnosis is mainly clinical and cases require urgent surgical exploration and primary repair

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Havelund JF, Heegaard NHH, Faergeman NJK, Gramsbergen JB (2017) Biomarker research in Parkinsons disease using metabolite profiling