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The alfapump system (AS), providing slow and continuous paracentesis via a subcutaneous pump, has been shown to be an alternative in selected patients

[51] [52] Oxidative stress also plays a role in the ischemic cascade due to oxygen reperfusion injury following hypoxia

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We elaborate on metabolic changes for macrophages, neutrophils, vascular endothelial cells, vascular smooth muscle cells and lymphocytes in the context of atherosclerosis and its co-morbidities hypertension, dyslipidemia, and diabetes