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The equilibrium constant Kd is: With mobile phase moving, protein molecules in mobile phase are carried forward and adsorbed by downstream medium, at same time adsorbed proteins are released from stationary phase to mobile phase

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Pyroptosis is characterized by DNA damage, cellular swelling, and consequent leakage of cellular contents, particularly pro-inflammatory cytokines, such as IL-1 and IL-18 [41, 46]

for example, the greatest fold changes for alanine were observed among the most sensitive cells to MTX, whereas 2-oxoglutarate (-ketoglutarate) greatest fold changes were found among the most resistant cells to the antifolate ( Figure 1C )