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We have bathed her twice, applied medication twice and the fleas persist. This pattern extends to veterinary medicine, where extended or improperly managed antibiotic courses in dogs treating chronic conditions such as recurrent skin infections contribute to antimicrobial resistance (21)

While elevated MMA blood concentration is considered the specific indicator of deficiency (19), other clinical assays are often used as biomarkers of vitamin B 12 status sometimes in combination

doi: 10.7554/eLife.17834

Subsequent interest in AOD-9604 has been limited to niche research areas, particularly osteoarthritis, where intra-articular injection might bypass systemic bioavailability limitations