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While rare, taking too much vitamin A, D, or E can lead to potentially harmful side effects ( Alternatively, taking high doses of non-synthetic vitamin K seems to be relatively harmless, which is why an upper intake level (UL) has not been set for this nutrient ( Upper intake levels are set to indicate the maximum dose of a nutrient thats unlikely to cause harm for nearly all people in a general population ( SUMMARY Water-soluble vitamins are readily excreted from the body, while fat-soluble vitamins can be stored in tissues

Mechanisms include reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression supporting neuronal survival, angiogenesis improving cerebral blood flow, and modulation of dopamine and serotonin systems

Bjog 2015;122:623-33

UCSF ChimeraX: structure visualization for researchers, educators, and developers